Jäntra Biosystems | Multiple Roles | San Francisco or Remote | Full-time | Salary + Equity

Jäntra Biosystems is revolutionizing protein structure prediction. We’re building AI models at the intersection of biology and computation. Join us as we unlock life’s molecular machinery.

Open Roles:

- AI Systems Engineer (C++ / CUDA / HPC)

- Structural Biologist / Bioinformatics Scientist (Cryo-EM / AlphaFold / Data Analysis)

What we’re looking for:

Engineers & scientists passionate about AI and biology. C++/CUDA expertise (AI Systems Engineer) or structural biology experience (Bioinformatics Scientist). Familiarity with HPC, GPU clusters, or structural prediction tools (AlphaFold, cryo-EM, etc.).

Why Jäntra: Competitive salary + equity San Francisco or remote Small, fast-moving team Work that matters: advance our understanding of life’s building blocks

Apply: https://jantra.ai/jobs.html email: Email is hidden

Mozilla | Remote (US) | Principal Eng

My team is hiring for a really exciting position at Mozilla! We’re looking for a founding technical lead on a browser-automation effort for AI systems. This role is in the New Products division and has a lot of agency and autonomy.

This role will shape the long-term architecture and roadmap, write production-grade code across multiple languages, and build the core distributed systems and tooling. This is a rare and unique opportunity to set the direction and guide a high-leverage team, all while helping shape the future of interaction on the web.

Full job post here: https://mozilla.org/en-us/careers/position/gh/7230082/

Email jervin [@] mozilla.com and mention that you saw this on Ask HN: Who is hiring.

Yuzu | https://yuzu.health | Engineers & Designers | Onsite in NYC | Full-time

At Yuzu, we’re building the next-generation health insurance company. We are NOT building a digital brokerage or an AI wrapper - we are going deeper to build the foundational infrastructure required to power tomorrow’s health plans.

We're hiring aggressively across the board, see open roles at https://yuzu.health/careers

Oryo.io | Founding Engineers / Staff Software Engineers | Cybersecurity | Remote (US, ideally near SF/Seattle/Boston) | Full-time | 180-220K + Equity & Benefits | No Visa sponsorship.

Oryo helps CISOs secure GenAI/Agentic AI. We enable enterprises to address AI tool misuse, privilege escalation, and AI supply chain risk, giving security teams the visibility and control to manage agent behavior and secure data access.

*Engineering challenges* - Build pipelines to monitor config + real-time agent behavior - Detect privilege escalation, tool misuse, attack paths, supply chain vulnerabilities, compliance risks - Explore gaps in protocols like MCP + A2A, interoperate with existing security stacks - Build AI-centric security products from 0→1 - Build using a variety of modern languages, frameworks and cloud and ai native architectures.

*You are* - Full-stack engineer with 5+ years experience in infra, data, or security systems - High bar for engineering excellence, ownership, and system design - Bonus: prior experience in cybersecurity, infra, data science, front end, or AI security

*Why join* - Competitive pay ($180–220k) + early equity - Remote with proximity to SF/Seattle/Boston - Work on a new frontier in security, where your judgment and code shape the company - Culture: respect, transparency, autonomy, and excellence

- More info : https://docsend.com/view/5xw8iv8y48wzztxw

To apply: email Email is hidden

StrongDM | [Staff, Senior, Junior] AI Agent Engineer | San Francisco Bay Area (Palo Alto) | Full-Time | ONSITE | SW3.0

StrongDM applies deep tech to hard problems for demanding cybersecurity customers. Our embrace of large language models continues that tradition, achieving useful and reliable outputs from ambiguous and non-deterministic inputs.

Join me (Justin, co-founder & CTO) and our AI Agent team to help our global customers secure their most critical systems.

Ideally: if you've already decided you need to be working on the frontier of this technology wave & you're open to doing so in person at a physical whiteboard, e-mail me a few words to that effect (Email is hidden).

Optionally: read more at http://strongdm.com/careers

Finally: on a personal note - a mix of awe, ambition, anxiety, and confusion are inevitable at this moment. Our small team has found a flow, and we're successfully metabolizing the daily changes in the gradient. Come on a run with us; see what we see.

Seeq | https://seeq.com | Staff/Principal Software Engineer (Full stack) | REMOTE (Some crossover w/ PST required) | Full-time | $170k - $200k + equity. Salary range for US-based; local adjustments for other countries. Seeq creates cutting-edge data analytics software for industrial process data, serving sectors like pharmaceuticals, energy, and manufacturing. Our core product is a robust calculation engine capable of executing advanced math and machine learning algorithms on streaming time-series data. By leveraging generative AI, we enhance usability and accelerate outcomes for our users. We've built up a great remote culture (e.g. annual meetups, a remote office app we created to collaborate) and a dev team that enjoys tackling hard problems that make a difference for our customers (dev blog for more: https://geeq.seeq.com/).

Staff Frontend/Full stack Engineer (React, Typescript, Kotlin): https://apply.workable.com/seeq/j/d08da1a63c/

Aesthetic | Full Stack | FULLY REMOTE | Full-time OR Contract | Cash + Equity

Aesthetic is a venture-backed consumer app that lets you dress like your favorite influencer at a fraction of the cost. We're currently sitting at around 200k users and scaling fast.

We're hiring for a couple of roles: - Senior Full Stack - Paid Engineering Internships

Tech Stack: - Expo - AWS(Lambda, OpenSearch, S3, DynamoDB) - Next.js - Supabase

Must Haves: - Self starter - Willing to work late hours - JS/TS fundamentals - Obsessed with learning

Interested? Email me your latest project: kevin [@] myaesthetic.ai

Try our product: https://www.instagram.com/myaesthetic.ai/

Moov | Multiple Roles | Remote (US Only)

Moov powers infinite payment use cases with full data transparency. However you decide to orchestrate the motion of money: pay by bank, pay by card, disburse to a Moov wallet or linked bank account with same-day ACH or RTP®, or spend with an issued card—we’ve got you covered.

"Moov has become an integral part of our strategy at Jack Henry. Their platform’s developer-first approach allows us to innovate quickly and stay ahead of industry demands. Moov’s world-class engineering and design team has deep experience navigating complex payment infrastructure, which helps us win because we’re able to focus on building exceptional customer experiences." – Ben Metz, CTO, Jack Henry

Our technology stack includes: Go, PostgreSQL, AlloyDB, Spanner, Kubernetes, Docker, GCP, OpenTelemetry, Kafka, and more.

Open Roles:

- Senior Software Engineer ($165k–$185k)

- Senior Software Engineer – Front End ($145k–$160k)

- Director of Risk Operations ($175k–$190k)

- Account Manager (Base $120k–$140k, Commission $60k, OTE $180k–$200k)

- Enterprise Account Executive (Base $155k–$175k, Commission $150k, OTE $305k–$325k)

Don't see your preferred role? Email Email is hidden with your resume.

Apply: https://moov.io/careers/#open-roles

Website: https://moov.io/

Actively AI| Multiple Roles | In office in NYC | Salary + Equity

What Cursor has done to revolutionize coding, we are looking to do for revenue. Every large company spends 40-50 cents of every dollar they earn on sales & marketing, and it’s very inefficient because data lives in so many different systems, sales reps are stretched thin doing manual work, and products are rapidly evolving.

It’s why we are building the agent and intelligence framework for enterprise scale GTM that guides every sales motion across the funnel — from SDR outreach to AE deal strategy to cross-sell and expansion. It’s an intelligence layer that sits on top of every sales tool and with external browsing that is then customized to your specific products & GTM motions.

It’s a massive technical challenge: - Intelligence at scale: modeling millions of accounts, real-time signals, and contextual history into per-account reasoning agents. - AI Agents & Chat: designing systems across “push” (recommendations) and “pull” (interactive assistants), with extensible skills customers can train themselves. - Data & Infrastructure: creating a new framework for real-time, per-customer agents that simplifies pipelines, scales efficiently, and cuts costs (we’ve already cut cost per account by 50% through smarter eval-driven approaches). - Wall-to-wall product: from self-serve UI to Slack integrations, from predictive models to generative copilots — we’re building an AI operating layer for GTM.

Why Join Engineering at Actively: - Customer-driven impact: engineers directly go onsite and spend time with customers, deploying agents that reshape workflows at companies like Samsara and Justworks. - Category creation: there’s a huge opportunity to build the pre-dominant AI company for GTM with a massive TAM - Cutting-edge AI: opportunity to push the frontier of reasoning agents, eval-driven development, and scalable intelligence. - High-caliber peers: we’re ex-Instacart, Scale AI, Stanford AI researchers, and operators who’ve built at scale before.

Open roles: https://www.actively.ai/careers

Parable | Multiple Roles | Fully remote or in office in NYC | Salary + Equity

Parable is the intelligence layer for enterprise operations, we help organizations understand how they are spending time and money and identify the most impactful opportunities for AI and create actionable plans.

We just closed a large $17M seed round, are in market with large enterprise customers, and are founded by a team of exited and experienced founders.

- Staff/Senior AI Engineer on Context Mining - $200K – $325K + equity

- Staff Engineer & Technical Lead – Ontology - $200K – $350K + equity

- Forward-Deployed Engineer - Raw Data - $200K – $325K + equity

- Staff Engineer - Raw Data - $200K – $325K + equity

- Technical Product Manager - Raw Data - $200K – $325K + equity

- RevOps Manager - Sales - $150K – $250K + equity

- Sales Director - Sales • NY Office • On-site - $150K – $300K + commission

Apply here! https://jobs.ashbyhq.com/parable

Website here https://www.askparable.com