Immunera | Principal Machine Learning Engineer | NYC area (hybrid) | Full-time | immunera.ai

Hey! I’m Maxim, cofounder/CEO of Immunera.

We're building blood tests that use gene sequencing and machine learning to help patients with autoimmune disease. Immunera spun out of years of research at Stanford, and our technology has been published in Science and covered by The New York Times.

We're hiring a Principal Machine Learning Engineer to shape the core models and infrastructure that power our blood tests. We are partnering with hospitals to generate training data from real patients for our language models and other biological sequence models.

This is a senior engineering role with significant autonomy at an early-stage, venture-backed startup. We're looking for strong experience building and operating ML systems in production (Python, PyTorch/TensorFlow, cloud platforms). Prior biology or healthcare experience is NOT required; we care much more about your ability to reason about data, models, and systems.

Full JD: https://www.immunera.ai/jobs

Contact: Email is hidden (subject: “HN ML job”)

Kadoa | Multiple roles | Remote | Full-Time | https://kadoa.com

We’re on a mission to give humans and LLMs reliable and fast access to web data.

Web scraping used to be the same for decades (brittle scripts that break constantly). We're automating that end-to-end with LLMs that build and maintain data pipelines. We're also heavily focused on making ethical scraping the default (robots.txt checks, rate limiting, etc.).

All 3 founders have spent years in the trenches writing web scraping and ETL software and still do it almost every single day. We’re making sure every team member can do the best work of their career at Kadoa.

We are looking for people who share our passion for software craftsmanship, data, and AI.

We are growing fast, have a no-bullshit culture, and try to minimize the distance between the code you write and the customers who use it.

We have openings for:

- Senior Frontend Engineer: https://www.kadoa.com/careers/frontend-engineer

- Senior Software Engineer: https://www.kadoa.com/careers/senior-software-engineer

If that sounds like you, please email me at (adrian at kadoa dot com) and mention HN in the subject line. AI slop applications will be filtered out immediately ;)

Stellar Science | Hybrid (USA) Albuquerque NM, Washington DC (Tysons VA), Dayton OH | Full time, interns/co-ops | U.S. citizenship required | https://www.stellarscience.com

Company: We're a small scientific software development company that develops custom scientific and engineering analysis applications in domains including: space situational awareness (monitoring the locations, health and status of on-orbit satellites), image simulation, high power microwave systems, modeling and simulation, laser systems modeling, AI/ML including physics-informed neural networks (PINN), human body thermoregulation, computer vision and image processing, high performance computing (HPC), computer aided design (CAD), and more. All exciting applications and no CRUD. We emphasize high quality code and lightweight processes that free software engineers to be productive.

Experience: Except for interns, we currently require a Bachelors degree in physics, engineering, math, computer science, or a related field. Masters or PhD is a plus. (Roughly 25% of our staff have PhDs.)

Technologies: Mostly C++23, Qt 6.9, CMake, git, OpenGL, CUDA, Boost, Jenkins. Windows and Linux, msvc/gcc/clang/clangcl. AI/ML and analysis projects use Python and C++. Some projects use Java or Typescript/React.

Apply online: at https://www.stellarscience.com/careers/.

DoShare Labs | India | Locations : New Delhi, Bangalore, NY(US) , SF(US) ,Remote Positions we're hiring for :

1. Technical Liaison :

Requirements:

2+ Years of Working in Tech Experience | Good Communication Skills | Bachelors or Equivalent Degree

2. Infrastructure Engineer :

Requirements:

3+ Years of Experience as Infra Engineer | Stack - Python, Go, Kubernetes, GCP/AWS/Azure , Cloudflare

3. Project Lead (UI/UX) :

3 + Years of Project Development Experience | Good understanding of market requirements | A/B Testing | Engineer or similar degree

4. Customer Support Executives [English OR Hindi]

2 Years of Customer Support Experience | Speaking Skills | Ability to follow tasks at hand

5. Marketing Posts (3 Positions)

Experience with Marketing and Advertisement | Out-of-the-box Thinking Ability | Led or Organised Events

Note: Keep the position you're applying for in the title.

Apply via Mail : Email is hidden

Marker | Full-time | Remote or Hybrid (NYC/SF/London) | https://markercollective.com

Marker is a technology venture from 3 leading communications agencies. We’re an incubator building and launching force-multiplying software products for communications teams.

Our first product is Delve (https://delve.news) — a coverage monitoring, analysis, and insight toolkit to track and measure the entire online conversation about your business or industry.

Our product team is small and autonomous, but with the resources, expertise, and customer access of the global agencies we work with. We’re hiring an early engineer to join us on this journey; you’ll have a large impact on what we build, how we build it, and where we’re going next.

Our current technology stack includes Deno, React, and PostgreSQL. Bonus points for expertise in any of: data visualization, distributed systems, web scraping, large-scale data pipelines.

Contact: dylan (at) company domain. No recruiters or agencies, please.

John Carroll University Faculty of Practice in Data Science

Cleveland OH | Onsite

To view the complete job description and apply, please visit: https://jcu.peopleadmin.com/postings/3954 * Only applications and inquiries through this website will be considered.

The Department of Mathematics, Computer Science, and Data Science (MCDS) at John Carroll University invites applications for a Faculty of Practice (open rank, non-tenure-track) position in Data Science. This is an exciting opportunity to shape the future of our growing Data Science and Analytics program and serve as a vital link between our students and industry. We welcome applicants from a broad range of data science specialty areas. Faculty rank and salary will be commensurate with experience and academic credentials. Full consideration will be given to applications that are complete by January 12, 2026, although applications will be accepted until the position is filled. The anticipated hire start date is August 2026.

In addition to teaching a variety of undergraduate courses, the successful candidate will play a critical leadership role in the development and growth of our Data Science and Analytics curriculum and student outcomes. They will also collaborate with the Career Center to help establish industry partnerships and serve as a mentor to students pursuing careers in data science and analytics. Service to the department and university is also a key component of this position.

Duties and Responsibilities The successful candidate will play a critical leadership role in the development and growth of our Data Science and Analytics curriculum and student outcomes, including: - Teach a variety of undergraduate courses. Potential courses include data mining, big data and cloud computing, or agentic development. - Assist with crafting and implementing a vision for the Data Science and Analytics program, guiding its strategic direction and evolution. - Keep up to date on trends in Data Science & Machine Learning, given traditional DS techniques are being handled by AI (e.g. exploratory data analysis, outlier detection, etc.). - Collaborate with the Career Center to help establish industry partnerships, serving as a key industry liaison to facilitate internships and career opportunities for students. - Mentor and advise students pursuing careers in data science and analytics. Contribute to departmental and university service, including participating in cross-university data initiatives.

Required Qualifications - A Master’s degree in a related field. - Experience communicating findings effectively in the professional world. - Interest and enthusiasm in working with undergraduate students in a liberal arts environment. - Familiarity with strong pedagogical practices, including active learning approaches.

Preferred Qualifications - Prior teaching experience as an instructor of record at the undergraduate level. - Industry experience in data science or an adjacent analytical field. - Evidence of effective teaching, training, or mentoring at the college level or in professional settings.

Pango | Founding Full-stack Software Engineer | On-site (hybrid) in Stockholm, Sweden (Visa Sponsorship possible) | Full time

Pango is building the world's first Agentic Operating System for e-commerce logistics. Our vision is to create the AI e-commerce employee of the future. We are forming our core team in Stockholm and are looking for exceptional engineers. We are based at the SSE Business Lab, where companies such as Klarna, Voi, Budbee or Legora originated. We have achieved a product-market fit and are growing rapidly.

You are a good fit if:

* You are comfortable maintaining, expanding and operating an entire B2B SaaS platform with a high sense of ownership.

* You are happy to take on work that in a large company is divided into a dozen roles, and execute it all at a good enough level.

* You are unafraid of any technology. If we need a desktop app and you haven't done one before, you will study the documentation of Electron.js and build one. If a model for predicting delivery times is needed, you will do a literature review to find the right architecture and train one.

* You have strong proficiency in any backend language or platform, with a strong willingness to dive deep into PHP/Laravel OR strong proficiency in JS/React.

* E-commerce (Shopify, Magento, other platforms, shipping carrier integrations) experience is a plus.

You will take a key role in shaping the product and company, with ability to make an impact and advance career limited only by your aptitude and interest.

Reach out to Email is hidden if you are interested or have any questions. We review applications immediately and move quickly.

FetLife | Senior DevOps Engineer | Full-Time | Remote | 115k - 180k USD - https://fetlife.com/jobs/devops-engineer

Role: Develop and implement infrastructure upgrades, database tuning, Kubernetes and Helm orchestration, monitoring, and security. Help maintain and improve our large-scale Rails monolith, including CI/CD. Participate in on-call rotation and help automate daily DevOps tasks.

Stack: MySQL/PostgreSQL, ScyllaDB, Redis, ElasticSearch, Terraform, Google Cloud, DataDog and more.

Applications: Rails, Vue.js/Typescript, Rust

Perks: Paid time off (2 weeks vacation, 5 statutory holidays, 2 weeks at Christmas, 4-day summer workweeks), annual company retreat, anniversary gift ($200/year), monthly music subscription reimbursement, fully paid maternity & paternity leave.

About Us: FetLife is the largest kinky social network with 10M+ members, 100% word-of-mouth growth, and billions of daily requests.

How to apply: Email Email is hidden with a brief introduction, 2–3 favorite projects, GitHub/GitLab link, and LinkedIn profile or resume (PDF).

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Senior Product Manager | Full-Time | Remote | $140k - $200k USD - https://fetlife.com/jobs/product-manager

Role: Understand member needs, craft detailed product pitches, drive discovery, reduce friction, own product metrics, and guide strategy to deliver meaningful value across our large-scale platform.

Perks: Paid time off (2 weeks vacation, 5 statutory holidays, 2 weeks at Christmas, 4-day summer workweeks), annual company retreat, anniversary gift ($200/year), monthly music subscription reimbursement, fully paid maternity & paternity leave.

How to Apply: Email Email is hidden with a brief introduction, 1-2 examples of measurable product impact, and LinkedIn or resume (PDF).

Piq Energy | Full Stack Software Engineer | SF, Athens, or US REMOTE | Full-time | $150k-$250k + equity (SF; location-adjusted)

https://jobs.gem.com/piqenergy/am9icg9zddp5j21vrwepgiuq005h6...

Piq Energy builds software that helps renewable and large-load developers get projects connected to the electric grid faster. We automate grid interconnection studies and planning workflows.

You’ll own features end-to-end: interactive frontend, backend APIs, data pipelines, AI agents, and power systems simulation workflows. We’re looking for experienced generalists who like ownership, real-world impact, and scaling startups.

Stack: Typescript, Svelte, GraphQL, Mapbox, D3.js, Python, LLM agents, Postgres, workflow orchestration

Clever Benefits | Scottsdale, AZ (Hybrid — 2 days/week onsite, North Scottsdale) | Full-time | $140k–$180k | Senior Full Stack (React/React Native/Node/AWS)

Clever Benefits is hiring a Senior Full Stack Software Engineer to help build and scale our platform. You’ll ship end-to-end features across a React web app, React Native mobile app, Node.js/TypeScript backend, and AWS infrastructure. Small team, high ownership, production focus.

Stack: TypeScript, React, React Native, Node.js, Prisma, PostgreSQL, tRPC, AWS (Lambda, ECS/Fargate, S3, RDS), CI/CD.

Requirements: 8+ years experience; strong TypeScript; production React + React Native + Node; solid AWS background; Prisma/Postgres/tRPC; comfortable owning features from design → deployment. Must live within 30 miles of North Scottsdale and be able to be onsite 2 days/week.

Nice to have: TestFlight/Play Store workflows; monorepos (pnpm/bun workspaces); IaC (CDK/Terraform). Interest in using AI to accelerate development (codegen/automation) — with an emphasis on maintainable, high-quality engineering.

How to apply: Email your resume + a short note (and links/GitHub if you have them) to Email is hidden with subject “HN — Senior Full Stack Engineer”.